Fertility is shaped by weight, metabolic health, menstrual regularity, ovarian function, age, sleep, other medications, and underlying conditions. For people with weight-related fertility problems, weight loss can support a return of regular cycles.

For people in a steep calorie deficit, fertility signals can shift the other way. That's a property of the deficit, not specific to these peptides.

Semaglutide labels such as Wegovy and Ozempic point to stopping at least two months before a planned pregnancy because of the long washout period.

The signal in the label is a planning window, not a proven human infertility outcome. Animal data suggest the pathway can affect ovulation biology at weight-loss-associated doses, so the honest claim is narrower: human infertility is not an established label outcome.